Neutralizing antibody evolution

Titration of Rinderpest Virus and Its Neutralizing Antibody

Pre-exposure Neutralizing Antibody

Maximilian Larena, Natalie A Prow, Roy A Hall, Nikolai Petrovsky and 6 Mario Lobigs 7 8 1 Department of Emerging Pathogens and Vaccines, John Curtin School of Medical 9 Research, The Australian National University, Canberra, Australia 10 2 Australian Infectious Diseases Research Centre, School of Chemistry and Molecular 11 Biosciences, The University of Queensland, St Lucia, Australia 12 3 Vaxi...

HIV vaccine design: the neutralizing antibody conundrum.

A brief historical overview of anti-HIV vaccine approaches The identification of the human immunodeficiency virus as the causative agent of AIDS [1–4] was followed by intensive efforts to develop a vaccine against this pathogen. Initial vaccine approaches aimed at the elicitation of anti-viral neutralizing antibodies (NAbs). The sole target of anti-HIV NAbs is the viral envelope glycoprotein (E...

Neutralizing antibody responses to varicella-zoster virus.

Neutralization of varicella-zoster (V-Z) virus by human sera and immune rhesus monkey sera was enhanced by fresh guinea pig complement. There was no marked difference in the degree to which complement enhanced neutralization by sera from current V-Z virus infections and sera from long-past varicella infections. Immunoglobulin G neutralizing antibody in sera from varicella cases was enhanced by ...

Neutralizing Antibody Response and SARS Severity

Using the Taiwan nationwide laboratory-confirmed severe acute respiratory syndrome (SARS) database, we analyzed neutralizing antibody in relation to clinical outcomes. With a linear mixed model, neutralizing antibody titer was shown to peak between week 5 and week 8 after onset and to decline thereafter, with a half-life of 6.4 weeks. Patients with a longer illness showed a lower neutralizing a...